Synthetic data only. Never enter patient information; nothing is sent or stored. For clinicians. Not FDA cleared.

CPE-008 · Safety

AI-13: Known adrenal insufficiency with intercurrent illness

Known adrenal insufficiency with intercurrent illness. Evaluates known adrenal insufficiency.

Active rulePriority 2Adrenal engine v1.0.0

Condition

  • known adrenal insufficiency
  • fever, vomiting, diarrhea, trauma or surgery

What it reports

  • Sick-day rules apply: glucocorticoid cover is increased per the patient's plan, and parenteral treatment is needed if vomiting

Diagnostic boundary

  • Dose and route belong to the treating physician and the patient's written plan.

Evidence

  • EV-ES-PAI-2016Bornstein SR, Allolio B, Arlt W, et al. Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2016;101(2):364-389.Supports: Morning cortisol and ACTH as first tests; ACTH stimulation with 250 µg cosyntropin; peak cortisol below 18 µg/dL as insufficient Suspected adrenal crisis must be treated without waiting for tests

Cases where this rule fires

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