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CPE-009 · Classification
B12-09: Blood film clue: hypersegmented neutrophils
Blood film clue: hypersegmented neutrophils. Evaluates hypersegmented neutrophils reported.
Active rulePriority 5B12 engine v1.0.0
Condition
- hypersegmented neutrophils reported
What it reports
- A supportive finding for a megaloblastic state
Diagnostic boundary
- Supportive only.
Evidence
- EV-BSH-2014Devalia V, Hamilton MS, Molloy AM; British Committee for Standards in Haematology. Guidelines for the diagnosis and treatment of cobalamin and folate disorders. Br J Haematol. 2014;166(4):496-513.Supports: Diagnostic approach with serum B12, MMA and homocysteine Neurologic involvement means treatment should not wait for confirmation Folic acid alone must not be given while B12 deficiency is unexcluded
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
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