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CPE-003 · synthetic case CKD-FX-011
Severe potassium elevation with eGFR unknown
Severe potassium elevation with eGFR unknown
Purpose: Fire global safety alert independently of CKD status
Inputs the engine received
Patient
- Age
- 64 years
Context
- Sex for equation
- male
- Hemolysisag
- unknown
Laboratory
- Potassium
- 6.4 mmol/L
What the engine reports
Assess symptoms, ECG and specimen validity urgently according to the local critical-value protocol. This alert does not depend on a CKD diagnosis.
Detected clinical pattern
Urgent Red Flag — Priority Safety Review
A safety rule requires urgent clinician review. Safety findings precede any classification.
Clinical summary
Priority safety finding: severe potassium elevation. Physician adjudication required.
Recommended next steps
For physician consideration. Urgent review always comes first.
- 1Urgent assessment of potassium: symptoms, ECG and specimen validity per local critical-value protocol.
Missing information
- UACR (required for the A category, risk assessment and a complete classification).
- Serum creatinine (or a reported eGFR).
Why it matters
The result is placed in context so the physician can see what is established, what is provisional and what is missing.
Evidence and rule trace · 2 rules
DQ-003Input units and specimen quality required
Inputs: potassium 6.4 mmol/L · hemolysis status unknown
data_quality_warning: assess sample hemolysis without delaying urgent review
SAFE-K-001Severe hyperkalemia independent of CKD classification
Inputs: potassium 6.4 mmol/L
urgent_red_flag
Evidence
- R1 · KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Disease: Improving Global Outcomes (KDIGO), 2024.
- R3 · eGFR Equations for Adults: 2021 CKD-EPI creatinine and creatinine-cystatin C race-free equations. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) / NIH, 2026.
Physician adjudication required. Clinical decision support for physician review. Criteria-based status is not a probability. Findings require physician adjudication and correlation with the complete clinical context. Validation-only release: not for production clinical use.
Change the values
The same engine, starting from this case. Change any value and watch the pattern and the rule trace react.
Live eGFR and CGA map
eGFR (mL/min/1.73 m²)
—
enter a creatinine
| GFR \ ALB | A1<30 | A230–300 | A3>300 |
|---|---|---|---|
| G1≥90 | |||
| G260–89 | |||
| G3a45–59 | |||
| G3b30–44 | |||
| G415–29 | |||
| G5<15 |
No cell is shown until there are data. Colors follow the KDIGO risk heat map: green low, yellow moderately increased, orange high, red very high.
Kidney functionAdd a prior result with dates to test chronicity
Switches the engine to the combined eGFRcr-cys equation.
Albuminuria
Chemistry
Kidney findings and red flags
Context
Transient albuminuria confounders
Creatinine may be unreliable
Complications (persistent)
Therapy
Documented history and special populations
This case also carries values that have no field here: eGFR_selected. They are included in the calculation until you clear the form.
More kidney cases
CKD-FX-001
Persistent moderately increased albuminuria with preserved GFR
Persistent moderately increased albuminuria with preserved GFR
CKD-FX-002
Persistent severely increased albuminuria with mildly decreased GFR
Persistent severely increased albuminuria with mildly decreased GFR
CKD-FX-003
Single reduced eGFR without chronicity
Single reduced eGFR without chronicity
CKD-FX-004
Acute creatinine rise before CKD staging
Acute creatinine rise before CKD staging
CKD-FX-005
Isolated suspected G3a requiring cystatin C confirmation support
Isolated suspected G3a requiring cystatin C confirmation support
CKD-FX-006
Combined eGFR reclassification support
Combined eGFR reclassification support
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