Synthetic data only. Never enter patient information; nothing is sent or stored. For clinicians. Not FDA cleared.

CPE-003 · Etiology patterns

CAUSE-004: Monoclonal protein-related kidney disease concern

Monoclonal protein-related kidney disease concern. Evaluates kidney abnormality detected is true.

Active rulePriority 73Kidney engine v1.2.0

Condition

  • All of:
  • kidney abnormality detected == true
  • Two or more of:
  • anemia present == true
  • hypercalcemia present == true
  • bone pain == true
  • non albumin predominant proteinuria == true
  • older adult == true

What it reports

  • Cause pattern: possible monoclonal protein related kidney disease
  • Clinician-directed serum/urine monoclonal protein evaluation and specialist review

Evidence

  • R1KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Disease: Improving Global Outcomes (KDIGO), 2024.Supports: CKD definition and chronicity CGA classification albuminuria confirmation risk prediction referral medication stewardship progression monitoring
  • R5KDIGO 2026 Clinical Practice Guideline for the Management of Anemia in CKD - Executive Summary. KDIGO, 2026.Supports: anemia thresholds first-line anemia workup iron deficiency terminology

Cases where this rule fires

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