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CPE-005 · Classification

LV-02: Steatosis not documented, fibrosis screening indicated

Steatosis not documented, fibrosis screening indicated. Evaluates steatosis not documented.

Active rulePriority 4Liver engine v1.0.0

Condition

  • steatosis not documented
  • type 2 diabetes OR prediabetes OR at least two cardiometabolic risk factors OR persistently raised ALT

What it reports

  • Screening opportunity: AASLD recommends FIB-4 in patients with these risk profiles

Recommended next steps (for physician review)

  • Calculate FIB-4
  • Consider liver imaging to document steatosis

Diagnostic boundary

  • Does not diagnose MASLD; steatosis must be documented.

Evidence

  • EV-AASLD-2023Rinella ME, Neuschwander-Tetri BA, Siddiqui MS, et al. AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease. Hepatology. 2023;77(5):1797-1835.Supports: FIB-4 first for risk stratification; thresholds <1.3 and >2.67; elastography 8 and 12 kPa; ELF 7.7 and 9.8 ALT upper limits near 29–33 U/L (men) and 19–25 U/L (women) Cardiovascular risk is the leading cause of death in MASLD

Cases where this rule fires

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