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CPE-005 · Fibrosis risk
LV-FIB-02: Elastography or ELF stratum
Elastography or ELF stratum. Evaluates liver stiffness (kPa) OR ELF score entered.
Active rulePriority 4Liver engine v1.0.0
Condition
- liver stiffness (kPa) OR ELF score entered
What it reports
- Stiffness below 8 kPa: low risk
- 8 to 12 kPa: indeterminate
- 12 kPa or above: high likelihood of advanced fibrosis
- ELF below 7.7 low, 7.7 to 9.8 intermediate, 9.8 or above high
Diagnostic boundary
- Cutoffs are device and assay specific.
Evidence
- EV-AASLD-2023Rinella ME, Neuschwander-Tetri BA, Siddiqui MS, et al. AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease. Hepatology. 2023;77(5):1797-1835.Supports: FIB-4 first for risk stratification; thresholds <1.3 and >2.67; elastography 8 and 12 kPa; ELF 7.7 and 9.8 ALT upper limits near 29–33 U/L (men) and 19–25 U/L (women) Cardiovascular risk is the leading cause of death in MASLD
- EV-EASL-NIT-2021European Association for the Study of the Liver. EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis, 2021 update. J Hepatol. 2021;75(3):659-689.Supports: Use of elastography and serum tests in sequence, and handling of discordant results
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
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