Synthetic data only. Never enter patient information; nothing is sent or stored. For clinicians. Not FDA cleared.

CPE-001 · synthetic case FX-015

No biochemical thyroid dysfunction with depression-like symptoms

Low mood, weight gain and fatigue, with TSH 3.2 and FT4 1.3.

Synthetic · no real patientReviewed acceptance scenarioThyroid engine v1.1.0

Purpose: Demonstrate restraint when symptoms lack thyroid biochemical pattern.

Inputs the engine received

Patient

Age and sex
45, female

Symptoms

Fatigue
Present
Weight gain
Present
Depressed mood
Present
Low libido
Present

Laboratory

TSH
3.2 mIU/L (ref 0.4–4.5)
FT4
1.3 ng/dL (ref 0.8–1.8)
ANTI-TPO
10 IU/mL (ref 0–35)
LDL-C
122 mg/dL (ref 0–100)
CK
88 U/L (ref 30–170)

What the engine reports

Detected clinical pattern

No Biochemical Evidence of Current Thyroid Dysfunction from Entered TSH and FT4

Thyroid-function tests entered are within their reported laboratory reference intervals.

Why this pattern was identified

  • TSH and FT4 within reference. TSH 3.2 mIU/L (ref 0.4–4.5) and FT4 1.3 ng/dL (ref 0.8–1.8).
  • Symptoms are supportive only. 4 compatible symptoms documented, but normal TSH and FT4 do not support a thyroid cause on their own.

Differentials, pitfalls and contradicting signals

  • Non-thyroid causes of the documented symptoms (mood disorder, sleep, anemia, metabolic or medication effects).
Evidence and rule trace · 0 rules

Physician adjudication required. For clinician review only. This output identifies clinical patterns and safety considerations from the documented inputs. It does not establish an autonomous diagnosis or treatment plan. Physician confirmation is required.

Change the values

The same engine, starting from this case. Change any value and watch the pattern and the rule trace react.

Thyroid-function testsMove the sliders or type values
  • below range
  • within range
  • above range
  • below range
  • within range
  • above range
TSH3.2 mIU/L · within reference
ref 0.44.5
Free T41.3 ng/dL · within reference
ref 0.81.8
Where this sits on the TSH × FT4 plane
Overt primarySubclinicalDiscordantCentral?EuthyroidDiscordantCentral?Low TSHThyrotoxicTSH ↑FT4 →

Zones are drawn from your reference intervals. The engine, not the map, decides the pattern.

Laboratory values and reference rangesUse your lab's own interval
Ref. low
Ref. high

µIU/mL and mIU/L are numerically identical.

Ref. low
Ref. high
Ref. low
Ref. high

Interpreted against the reporting assay's upper limit.

Ref. low
Ref. high

Only used in the thyrotoxicosis pathway.

Ref. low
Ref. high
Ref. low
Ref. high
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Ref. low
Ref. high
Patient context
Sex at birth
Medications and exposures
Symptoms and physical findingsSupportive only: never classify on their own

Symptoms

Signs and decompensation red flags

Live result · computed in your browser

Detected clinical pattern

No Biochemical Evidence of Current Thyroid Dysfunction from Entered TSH and FT4

Thyroid-function tests entered are within their reported laboratory reference intervals.

Why this pattern was identified

  • TSH and FT4 within reference. TSH 3.2 mIU/L (ref 0.4–4.5) and FT4 1.3 ng/dL (ref 0.8–1.8).
  • Symptoms are supportive only. 4 compatible symptoms documented, but normal TSH and FT4 do not support a thyroid cause on their own.

Differentials, pitfalls and contradicting signals

  • Non-thyroid causes of the documented symptoms (mood disorder, sleep, anemia, metabolic or medication effects).
Evidence and rule trace · 0 rules

Physician adjudication required. For clinician review only. This output identifies clinical patterns and safety considerations from the documented inputs. It does not establish an autonomous diagnosis or treatment plan. Physician confirmation is required.

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