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CPE-008 · Context triggers
AI-11: Immune checkpoint inhibitor
Immune checkpoint inhibitor. Evaluates checkpoint inhibitor treatment.
Active rulePriority 2Adrenal engine v1.0.0
Condition
- checkpoint inhibitor treatment
- fatigue, headache, nausea, weakness, hyponatremia or hypotension
What it reports
- Hypophysitis and primary adrenalitis are recognized immune-related adverse events: screen cortisol, ACTH, TSH, free T4 and sodium/potassium
Diagnostic boundary
- Reporting and management belong to the treating oncology team.
Evidence
- EV-ASCO-IRAE-2021Schneider BJ, Naidoo J, Santomasso BD, et al. Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: ASCO Guideline Update. J Clin Oncol. 2021;39(36):4073-4126.Supports: Endocrine immune-related adverse events: hypophysitis and adrenal insufficiency
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
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