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CPE-008 · Context triggers
AI-14: DHEA-S low for age
DHEA-S low for age. Evaluates DHEA-S below the age- and sex-specific reference.
Active rulePriority 6Adrenal engine v1.0.0
Condition
- DHEA-S below the age- and sex-specific reference
- fatigue or secondary pattern
What it reports
- Low DHEA-S supports ACTH deficiency
Diagnostic boundary
- Age-dependent and supportive only; not a screening test.
Evidence
- EV-ES-HYPOPIT-2016Fleseriu M, Hashim IA, Karavitaki N, et al. Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2016;101(11):3888-3921.Supports: Assess the adrenal axis before thyroid replacement in central hypothyroidism Secondary adrenal insufficiency testing
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
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