Synthetic data only. Never enter patient information; nothing is sent or stored. For clinicians. Not FDA cleared.For licensed clinicians. Educational demonstration on synthetic data. Never enter real patient identifiers or protected health information: everything runs in your browser and nothing is sent or stored. Clinical decision support only; not FDA cleared; physician review is required.
CPE-011 · synthetic case ANEM-FX-09
Hemoglobin 6.4 g/dL
Severe anemia.
Purpose: Severe anemia.
Inputs the engine received
CBC and reticulocytes
- Hemoglobin
- 6.4 g/dL
- MCV
- 68 fL
Patient
- Age
- 52 years
- Sex
- Female
What the engine reports
Hemoglobin is in a range that needs same-day clinical assessment. Transfusion and other treatment decisions belong to the treating physician.
Detected clinical pattern
Urgent Review Finding
A safety rule calls for urgent clinical assessment. Read the safety findings first.
- Severity: Severe anemia (Hb 6.4 g/dL)
- Morphology: Microcytic (MCV <80)
- Pattern: micro anemia unclassified
Recommended next steps
For physician consideration. Urgent review always comes first.
- 1Urgent clinical assessment of severe anemia.
Missing information
- Reticulocyte percentage with hematocrit (marrow response).
- Ferritin (and transferrin saturation).
Evidence and rule trace · 4 rules
AN-MISS-01Information needed
Inputs: Reticulocyte percentage with hematocrit · Ferritin
First-line studies are incomplete.
Evidence
- EV-WHO-HB-2011 · World Health Organization. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Geneva: WHO; 2011.
- EV-TEFFERI-2003 · Tefferi A. Anemia in adults: a contemporary approach to diagnosis. Mayo Clin Proc. 2003;78(10):1274-1280.
Physician adjudication required. Clinical decision support for physician review. This output classifies anemia by morphology and marrow response and lists patterns and safety considerations. It does not diagnose a cause, rank causes by probability, or select treatment or transfusion. Physician adjudication is required.
Change the values
The same engine, starting from this case. Change any value and watch the pattern and the rule trace react.
Morphology
● Microcytic
MCV <80 fL
○ Normocytic
MCV 80–100 fL
○ Macrocytic
MCV >100 fL
Marrow response (reticulocyte production index)
○ Inadequate · RPI <2
Hypoproliferative: deficiency, inflammation, kidney, marrow
○ Appropriate · RPI ≥2
Blood loss, hemolysis or recovery
No stage is assigned for the values entered.
CBC and reticulocytes
- <7
- 7–8
- 8–11
- 11–13
- ≥13
Patient
Iron, vitamins and inflammation
Hemolysis, kidney and thyroid
250 U/L is assumed when empty.
Blood film and other context
More anemia cases
ANEM-FX-01
Microcytic anemia with low ferritin
A 36-year-old, Hb 9.9, MCV 72, ferritin 6, TSAT 7%.
ANEM-FX-02
Microcytic anemia, normal iron indices and a low Mentzer index
MCV 62, RBC 5.7.
ANEM-FX-03
Macrocytic anemia with low B12 and hypersegmented neutrophils
MCV 112.
ANEM-FX-04
Hemolysis: reticulocytes 12%, LDH 640, haptoglobin 5
Spherocytes and a positive DAT.
ANEM-FX-05
Anemia in CKD
eGFR 28, normocytic, low reticulocytes, iron replete.
ANEM-FX-06
Anemia of inflammation
CRP 30, ferritin 340, TSAT 12%.
Try Biod in your practice
The Clinical Intelligence Layer — transforming fragmented clinical information into structured intelligence for clinician review and action.