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CPE-011 · synthetic case ANEM-FX-17
No anemia
Hemoglobin 14.1.
Purpose: Hemoglobin 14.1.
Inputs the engine received
CBC and reticulocytes
- Hemoglobin
- 14.1 g/dL
- MCV
- 90 fL
Patient
- Age
- 38 years
- Sex
- Male
What the engine reports
Detected clinical pattern
No Anemia by WHO Thresholds
Hemoglobin 14.1 g/dL is at or above the 13 g/dL threshold. Safety rules still apply.
- Severity: No anemia (Hb 14.1 g/dL)
Evidence and rule trace · 0 rules
Physician adjudication required. Clinical decision support for physician review. This output classifies anemia by morphology and marrow response and lists patterns and safety considerations. It does not diagnose a cause, rank causes by probability, or select treatment or transfusion. Physician adjudication is required.
Change the values
The same engine, starting from this case. Change any value and watch the pattern and the rule trace react.
Morphology
○ Microcytic
MCV <80 fL
○ Normocytic
MCV 80–100 fL
○ Macrocytic
MCV >100 fL
No stage is assigned for the values entered.
Marrow response (reticulocyte production index)
○ Inadequate · RPI <2
Hypoproliferative: deficiency, inflammation, kidney, marrow
○ Appropriate · RPI ≥2
Blood loss, hemolysis or recovery
No stage is assigned for the values entered.
CBC and reticulocytes
- <7
- 7–8
- 8–11
- 11–13
- ≥13
Patient
Iron, vitamins and inflammation
Hemolysis, kidney and thyroid
250 U/L is assumed when empty.
Blood film and other context
More anemia cases
ANEM-FX-01
Microcytic anemia with low ferritin
A 36-year-old, Hb 9.9, MCV 72, ferritin 6, TSAT 7%.
ANEM-FX-02
Microcytic anemia, normal iron indices and a low Mentzer index
MCV 62, RBC 5.7.
ANEM-FX-03
Macrocytic anemia with low B12 and hypersegmented neutrophils
MCV 112.
ANEM-FX-04
Hemolysis: reticulocytes 12%, LDH 640, haptoglobin 5
Spherocytes and a positive DAT.
ANEM-FX-05
Anemia in CKD
eGFR 28, normocytic, low reticulocytes, iron replete.
ANEM-FX-06
Anemia of inflammation
CRP 30, ferritin 340, TSAT 12%.
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