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CPE-004 · Anemia
ID-12: Iron deficiency without anemia
Iron deficiency without anemia. Evaluates no anemia.
Condition
- no anemia
- an iron-deficiency criterion met (ID-ST-01, ID-ST-02, ID-ST-04 or ID-ST-06)
What it reports
- Biochemical pattern compatible with iron deficiency without anemia (stage 1 or 2)
Diagnostic boundary
- A normal CBC does not exclude it. Symptoms such as fatigue are non-specific and are not attributed to iron by this rule.
Evidence
- EV-CAMASCHELLA-2015Camaschella C. Iron-deficiency anemia. N Engl J Med. 2015;372(19):1832-1843.Supports: Stages of iron deficiency, causes and differential diagnosis of microcytic anemia
- EV-LOPEZ-2016Lopez A, Cacoub P, Macdougall IC, Peyrin-Biroulet L. Iron deficiency anaemia. Lancet. 2016;387(10021):907-916.Supports: Risk groups, causes and evaluation of iron deficiency anemia
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
IRON-FX-02
Normal CBC, low ferritin, fatigue and hair loss
A 29-year-old with a normal CBC and a ferritin of 18.
IRON-FX-08
Heart failure with ferritin 82
A 70-year-old man with heart failure and a normal hemoglobin.
IRON-FX-22
Ice craving with a ferritin of 22
Pagophagia and a low ferritin.
IRON-FX-25
Iron-deficient erythropoiesis before anemia
Hb 12.4 but TSAT 11% and reticulocyte Hb 25 pg.
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