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CPE-003 · GFR estimation
GFR-003: Suggest cystatin C / combined eGFR for isolated possible G3a
Suggest cystatin C / combined eGFR for isolated possible G3a. Evaluates eGFRcr 2021 at or above 45.
Condition
- All of:
- eGFRcr 2021 >= 45
- eGFRcr 2021 < 60
- uacr mg g < 30
- other kidney damage marker == false
- cystatin c mg l missing
What it reports
- Action: Consider cystatin C for eGFRcr-cys confirmation before final isolated G3a classification, where available and clinically relevant.
Evidence
- R1KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Disease: Improving Global Outcomes (KDIGO), 2024.Supports: CKD definition and chronicity CGA classification albuminuria confirmation risk prediction referral medication stewardship progression monitoring
- R3eGFR Equations for Adults: 2021 CKD-EPI creatinine and creatinine-cystatin C race-free equations. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) / NIH, 2026.Supports: eGFRcr computation eGFRcr-cys computation assay standardization adult eligibility
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
CKD-FX-003
Single reduced eGFR without chronicity
Single reduced eGFR without chronicity
CKD-FX-004
Acute creatinine rise before CKD staging
Acute creatinine rise before CKD staging
CKD-FX-005
Isolated suspected G3a requiring cystatin C confirmation support
Isolated suspected G3a requiring cystatin C confirmation support
CKD-EX-04
Documented prior CKD supports chronicity
A single eGFR of about 50 in a patient with CKD documented years ago.
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