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CPE-010 · Exclusions
PC-07: Raised prolactin
Raised prolactin. Evaluates prolactin above the laboratory upper limit.
Active rulePriority 2PCOS engine v1.0.0
Condition
- prolactin above the laboratory upper limit
What it reports
- Hyperprolactinemia can cause irregular cycles: PCOS cannot be assigned until it is addressed
Diagnostic boundary
- Does not name the cause.
Evidence
- EV-PCOS-2023Teede HJ, Tay CT, Laven JJE, et al. Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2023;108(10):2447-2469.Supports: Adult diagnosis: irregular cycles plus hyperandrogenism once other causes are excluded; ultrasound or AMH when one is missing Adolescent criteria require both irregular cycles and hyperandrogenism Glycemic, cardiometabolic, sleep and mood assessment; endometrial risk in prolonged anovulation
- EV-ES-PRL-2011Melmed S, Casanueva FF, Hoffman AR, et al. Diagnosis and treatment of hyperprolactinemia: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2011;96(2):273-288.Supports: Hyperprolactinemia as a cause of oligo-amenorrhea
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
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