Synthetic data only. Never enter patient information; nothing is sent or stored. For clinicians. Not FDA cleared.

CPE-010 · Safety

PC-11: Prolonged amenorrhea

Prolonged amenorrhea. Evaluates amenorrhea for more than 3 months OR fewer than 4 cycles a year.

Active rulePriority 3PCOS engine v1.0.0

Condition

  • amenorrhea for more than 3 months OR fewer than 4 cycles a year

What it reports

  • Prolonged anovulation raises the risk of endometrial hyperplasia: the physician should consider endometrial assessment and protection

Diagnostic boundary

  • The engine names no regimen.

Evidence

  • EV-PCOS-2023Teede HJ, Tay CT, Laven JJE, et al. Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2023;108(10):2447-2469.Supports: Adult diagnosis: irregular cycles plus hyperandrogenism once other causes are excluded; ultrasound or AMH when one is missing Adolescent criteria require both irregular cycles and hyperandrogenism Glycemic, cardiometabolic, sleep and mood assessment; endometrial risk in prolonged anovulation
  • EV-ACOG-PCOS-2018American College of Obstetricians and Gynecologists. Polycystic Ovary Syndrome. ACOG Practice Bulletin No. 194. Obstet Gynecol. 2018;131(6):e157-e171.Supports: Clinical approach, exclusions and long-term risks

Cases where this rule fires

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