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CPE-010 · Calculations
PC-17: Free androgen index
Free androgen index. Evaluates total testosterone and SHBG available.
Context moduleContextPCOS engine v1.0.0
Condition
- total testosterone and SHBG available
What it reports
- Free androgen index = total testosterone (nmol/L) ÷ SHBG (nmol/L) × 100
- A low SHBG can reveal hyperandrogenism despite a normal total testosterone
Diagnostic boundary
- Informational; cutoffs vary by assay.
Evidence
- EV-PCOS-2023Teede HJ, Tay CT, Laven JJE, et al. Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2023;108(10):2447-2469.Supports: Adult diagnosis: irregular cycles plus hyperandrogenism once other causes are excluded; ultrasound or AMH when one is missing Adolescent criteria require both irregular cycles and hyperandrogenism Glycemic, cardiometabolic, sleep and mood assessment; endometrial risk in prolonged anovulation
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
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