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CPE-006 · Classification
HG-15: Testosterone not low despite symptoms
Testosterone not low despite symptoms. Evaluates total testosterone above 350 ng/dL.
Active rulePriority 5Testosterone engine v1.0.0
Condition
- total testosterone > 350 ng/dL
- symptoms documented
What it reports
- No biochemical testosterone deficiency from the value entered: non-specific symptoms have other causes
Recommended next steps (for physician review)
- Consider other causes of the symptoms (depression, sleep disorders, thyroid disease, anemia, medications)
Diagnostic boundary
- A normal value in one sample does not rule out all androgen problems.
Evidence
- EV-ES-TRT-2018Bhasin S, Brito JP, Cunningham GR, et al. Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2018;103(5):1715-1744.Supports: Diagnose with symptoms plus unequivocally low testosterone on two morning fasting samples Contraindications and cautions to therapy; monitoring of hematocrit and PSA Evaluation of the type of hypogonadism with LH and FSH
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
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