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CPE-006 · Classification
HG-05: Primary (hypergonadotropic) pattern
Primary (hypergonadotropic) pattern. Evaluates low total testosterone.
Active rulePriority 4Testosterone engine v1.0.0
Condition
- low total testosterone
- LH or FSH above the laboratory upper limit
What it reports
- Pattern of primary testicular failure: testes are the likely site
Recommended next steps (for physician review)
- Consider the causes of primary hypogonadism (for example Klinefelter syndrome, prior orchitis, cryptorchidism, chemotherapy or radiation, trauma)
Diagnostic boundary
- A pattern, not a cause.
Evidence
- EV-ES-TRT-2018Bhasin S, Brito JP, Cunningham GR, et al. Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2018;103(5):1715-1744.Supports: Diagnose with symptoms plus unequivocally low testosterone on two morning fasting samples Contraindications and cautions to therapy; monitoring of hematocrit and PSA Evaluation of the type of hypogonadism with LH and FSH
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
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