Start Free

Synthetic data only. Never enter patient information; nothing is sent or stored. For clinicians. Not FDA cleared.

CPE-010 · synthetic case PCOS-FX-03

Hyperandrogenism and polycystic ovaries with regular cycles

Ovulatory phenotype.

Synthetic · no real patientAuthored by Biod · reviewed by Dr. AmaralPCOS engine v1.0.0

Purpose: Ovulatory phenotype.

Inputs the engine received

Cycles and clinical signs

Age
31 years
Years since menarche
18 years
Usual cycle length
29 days
Hirsutism, modified Ferriman–Gallwey score
8

Laboratory and imaging

TSH
1.8 mIU/L
Prolactin
12 ng/mL
17-hydroxyprogesterone (early follicular, morning)
60 ng/dL
Ovarian volume
11.5 mL

Cardiometabolic, sleep, mood and fertility

BMI
31 kg/m²
Months since last glycemic assessment
6 months
Depression and anxiety screening done
Yes

What the engine reports

Detected clinical pattern

Pattern Meeting the 2023 PCOS Criteria

Criteria are met and other causes are excluded. A pattern for physician review; the work-up of cardiometabolic risk, sleep, mood and fertility follows.

  • Criteria met: 2 of 3 criteria

Why this pattern was identified

  • Criteria. 2 of 3 criteria are met (hyperandrogenism; polycystic morphology or raised AMH), and other causes have been excluded.

Recommended next steps

For physician consideration. Urgent review always comes first.

  1. 1Assess BMI and waist, blood pressure and a lipid profile; the metabolic engine applies the metabolic-syndrome criteria.
  2. 2Consider screening for obstructive sleep apnea.

Missing information

  • Total testosterone with SHBG (high-quality assay).
Evidence and rule trace · 6 rules

PC-03Criterion: hyperandrogenism

Inputs: hirsutism mFG 8

Clinical or biochemical hyperandrogenism.

PC-04Criterion: polycystic ovarian morphology or raised AMH

Inputs: ovarian volume 11.5 mL

Polycystic ovarian morphology or raised AMH.

PC-05PCOS criteria met

Inputs: 2 of 3 criteria · exclusions completed

Pattern meeting the 2023 international PCOS criteria.

PC-MISS-01Information needed

Inputs: work-up incomplete

The tests needed to complete criteria and exclusions are not all entered.

PC-13Cardiometabolic assessment

Inputs: PCOS criteria met

Cardiometabolic assessment.

PC-18Sleep-apnea screening

Inputs: BMI 31

Consider screening for obstructive sleep apnea.

Evidence

  • EV-PCOS-2023 · Teede HJ, Tay CT, Laven JJE, et al. Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2023;108(10):2447-2469.
  • EV-ROTTERDAM-2004 · Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004;19(1):41-47.
  • EV-ES-HIRSUTISM-2018 · Martin KA, Anderson RR, Chang RJ, et al. Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2018;103(4):1233-1257.

Physician adjudication required. Clinical decision support for physician review. This output applies published criteria to the values entered. It does not diagnose, exclude other causes by itself, or choose contraception, ovulation induction or any treatment. Physician adjudication is required.

Change the values

The same engine, starting from this case. Change any value and watch the pattern and the rule trace react.

Criteria met (adults need 2 of 3)

  1. ✓ 0 of 3

    No criterion met

  2. ✓ 1 of 3

    Not enough

  3. ● 2 of 3

    Criteria met if causes are excluded

  4. ○ 3 of 3

    All three present

Cycles and clinical signs

6 or more (4 or more in some ethnicities).

Laboratory and imaging

25 ng/mL is assumed when empty.

Endovaginal ultrasound. Not used in adolescents.

Cardiometabolic, sleep, mood and fertility

Live result · computed in your browser

Detected clinical pattern

Pattern Meeting the 2023 PCOS Criteria

Criteria are met and other causes are excluded. A pattern for physician review; the work-up of cardiometabolic risk, sleep, mood and fertility follows.

  • Criteria met: 2 of 3 criteria

Why this pattern was identified

  • Criteria. 2 of 3 criteria are met (hyperandrogenism; polycystic morphology or raised AMH), and other causes have been excluded.

Recommended next steps

For physician consideration. Urgent review always comes first.

  1. 1Assess BMI and waist, blood pressure and a lipid profile; the metabolic engine applies the metabolic-syndrome criteria.
  2. 2Consider screening for obstructive sleep apnea.

Missing information

  • Total testosterone with SHBG (high-quality assay).
Evidence and rule trace · 6 rules

PC-03Criterion: hyperandrogenism

Inputs: hirsutism mFG 8

Clinical or biochemical hyperandrogenism.

PC-04Criterion: polycystic ovarian morphology or raised AMH

Inputs: ovarian volume 11.5 mL

Polycystic ovarian morphology or raised AMH.

PC-05PCOS criteria met

Inputs: 2 of 3 criteria · exclusions completed

Pattern meeting the 2023 international PCOS criteria.

PC-MISS-01Information needed

Inputs: work-up incomplete

The tests needed to complete criteria and exclusions are not all entered.

PC-13Cardiometabolic assessment

Inputs: PCOS criteria met

Cardiometabolic assessment.

PC-18Sleep-apnea screening

Inputs: BMI 31

Consider screening for obstructive sleep apnea.

Evidence

  • EV-PCOS-2023 · Teede HJ, Tay CT, Laven JJE, et al. Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2023;108(10):2447-2469.
  • EV-ROTTERDAM-2004 · Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004;19(1):41-47.
  • EV-ES-HIRSUTISM-2018 · Martin KA, Anderson RR, Chang RJ, et al. Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2018;103(4):1233-1257.

Physician adjudication required. Clinical decision support for physician review. This output applies published criteria to the values entered. It does not diagnose, exclude other causes by itself, or choose contraception, ovulation induction or any treatment. Physician adjudication is required.

More pcos cases

PCOS-FX-01

Irregular cycles and hirsutism, exclusions complete

A 26-year-old with 8 cycles a year and an mFG of 9.

PCOS-FX-02

Irregular cycles and polycystic ovaries

No hyperandrogenism, 22 follicles per ovary.

PCOS-FX-04

Irregular cycles only

One criterion is not enough.

PCOS-FX-05

Criteria met, no exclusion tests

TSH, prolactin and 17-OHP missing.

PCOS-FX-06

Prolactin 68 ng/mL

Another cause of oligomenorrhea.

PCOS-FX-07

TSH 9.2 mIU/L

Thyroid disease explains irregular cycles.

All pcos cases

Try Biod in your practice

The Clinical Intelligence Layer — transforming fragmented clinical information into structured intelligence for clinician review and action.

Start Free for 3 Months (opens in a new tab)Send us a message

Contact Biod