Synthetic data only. Never enter patient information; nothing is sent or stored. For clinicians. Not FDA cleared.For licensed clinicians. Educational demonstration on synthetic data. Never enter real patient identifiers or protected health information: everything runs in your browser and nothing is sent or stored. Clinical decision support only; not FDA cleared; physician review is required.
CPE-006 · Calculations
HG-CALC-01: Calculated free testosterone
Calculated free testosterone. Evaluates total testosterone and SHBG available.
Condition
- total testosterone and SHBG available
What it reports
- Free testosterone by the Vermeulen equation (albumin 4.3 g/dL assumed unless entered)
Diagnostic boundary
- No threshold is applied.
Evidence
- EV-VERMEULEN-1999Vermeulen A, Verdonck L, Kaufman JM. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab. 1999;84(10):3666-3672.Supports: Calculated free testosterone from total testosterone, SHBG and albumin
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
TESTO-FX-03
Low on two samples with a primary pattern
Testosterone 205 and 190 with LH 22 and FSH 31.
TESTO-FX-04
Secondary pattern with obesity and diabetes
LH 1.2 and FSH 2.0 with BMI 36.
TESTO-FX-07
Borderline total testosterone
Total testosterone 320 with SHBG 62 and symptoms.
TESTO-FX-11
Chronic opioid use
Testosterone 210 and 200 with a low-normal LH.
TESTO-FX-12
Fertility desired
Low testosterone in a man trying to conceive.
TESTO-FX-13
Therapy under consideration: hematocrit 52% and PSA 5.2
Cautions to review before any decision.
TESTO-FX-17
Low testosterone with osteoporosis
A fragility fracture and two low values.
TESTO-FX-22
Two low values, no symptoms
A biochemical finding without compatible symptoms.
Try Biod in your practice
The Clinical Intelligence Layer — transforming fragmented clinical information into structured intelligence for clinician review and action.