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CPE-004 · Iron status
ID-ST-04: Iron deficiency likely despite inflammation
Iron deficiency likely despite inflammation. Evaluates inflammation documented or hs-CRP above 5 mg/L.
Active rulePriority 4Iron engine v1.0.0
Condition
- inflammation documented or hs-CRP above 5 mg/L
- ferritin < 70 ng/mL
Supportive, not required
- transferrin saturation < 20%
What it reports
- Iron deficiency likely coexisting with inflammation
Diagnostic boundary
- Ferritin is partly raised by inflammation, so the cutoff is higher than without it.
Evidence
- EV-WHO-FERR-2020World Health Organization. WHO guideline on use of ferritin concentrations to assess iron status in individuals and populations. Geneva: WHO; 2020.Supports: Ferritin below 15 µg/L indicates iron deficiency in healthy adults A higher cutoff (<70 µg/L) applies in the presence of infection or inflammation
Cases where this rule fires
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