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CPE-004 · Iron status
ID-ST-02: Low ferritin (15 to 29)
Low ferritin (15 to 29). Evaluates ferritin 15 to 29 ng/mL.
Active rulePriority 4Iron engine v1.0.0
Condition
- ferritin 15 to 29 ng/mL
- no inflammation changing the cutoff
What it reports
- Low ferritin: iron deficiency likely in the right context
- Below the 30 ng/mL level many guidelines use, even when the lab flags it as normal
Diagnostic boundary
- Interpret with symptoms, hemoglobin and transferrin saturation.
Evidence
- EV-WHO-FERR-2020World Health Organization. WHO guideline on use of ferritin concentrations to assess iron status in individuals and populations. Geneva: WHO; 2020.Supports: Ferritin below 15 µg/L indicates iron deficiency in healthy adults A higher cutoff (<70 µg/L) applies in the presence of infection or inflammation
- EV-AGA-2020Ko CW, Siddique SM, Patel A, et al. AGA Clinical Practice Guidelines on the Gastrointestinal Evaluation of Iron Deficiency Anemia. Gastroenterology. 2020;159(3):1085-1094.Supports: A ferritin cutoff of 45 ng/mL is suggested to diagnose iron deficiency Bidirectional endoscopy is suggested for asymptomatic men and postmenopausal women with iron-deficiency anemia Celiac serology and H. pylori testing have a role in evaluation
- EV-ACOG-ANEMIA-2021American College of Obstetricians and Gynecologists. Anemia in Pregnancy. ACOG Practice Bulletin No. 233. Obstet Gynecol. 2021;138(2):e55-e64.Supports: Pregnancy anemia thresholds; ferritin below 30 ng/mL suggests iron deficiency in pregnancy
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
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