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CPE-003 · Medication safety
MED-MET-001: Metformin renal impairment labeling flag
Metformin renal impairment labeling flag. Evaluates medication active is metformin.
Active rulePriority 100Kidney engine v1.2.0
Condition
- All of:
- medication active == metformin
- eGFR selected < 30
What it reports
- Medication flag: metformin contraindicated by renal function label
- Alert level: high
- Message: Metformin labeling contraindicates use below eGFR 30 mL/min/1.73 m2; clinician medication review required.
Evidence
- R8GLUCOPHAGE / GLUCOPHAGE XR Prescribing Information - Renal Impairment Recommendations. U.S. Food and Drug Administration (FDA) - Drugs@FDA labeling, 2017.Supports: metformin medication safety thresholds
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
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