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CPE-003 · Medication safety
MED-NEPHRO-001: Potential nephrotoxin exposure flag
Potential nephrotoxin exposure flag. Evaluates kidney abnormality detected is true.
Active rulePriority 105Kidney engine v1.2.0
Condition
- All of:
- kidney abnormality detected == true
- Any of:
- NSAID active or requested == true
- aminoglycoside active == true
- vancomycin active == true
- iodinated contrast planned == true
- other nephrotoxin active == true
What it reports
- Medication flag: renal risk medication review
- Message: Potential renal-risk medication or exposure detected; review indication, dose, interactions, monitoring and alternatives. Do not automatically label as contraindicated.
Evidence
- R1KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Disease: Improving Global Outcomes (KDIGO), 2024.Supports: CKD definition and chronicity CGA classification albuminuria confirmation risk prediction referral medication stewardship progression monitoring
- R8GLUCOPHAGE / GLUCOPHAGE XR Prescribing Information - Renal Impairment Recommendations. U.S. Food and Drug Administration (FDA) - Drugs@FDA labeling, 2017.Supports: metformin medication safety thresholds
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
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