Synthetic data only. Never enter patient information; nothing is sent or stored. For clinicians. Not FDA cleared.

CPE-003 · Medication safety

MED-MET-002: Metformin initiation/continuation review zone

Metformin initiation/continuation review zone. Evaluates medication active or proposed is metformin.

Active rulePriority 101Kidney engine v1.2.0

Condition

  • All of:
  • medication active or proposed == metformin
  • eGFR selected >= 30
  • eGFR selected < 45

What it reports

  • Medication flag: metformin renal review zone
  • Message: Do not initiate in the eGFR 30-45 range per labeling; if already taking, assess benefit-risk of continuing. Verify current product labeling.

Evidence

  • R8GLUCOPHAGE / GLUCOPHAGE XR Prescribing Information - Renal Impairment Recommendations. U.S. Food and Drug Administration (FDA) - Drugs@FDA labeling, 2017.Supports: metformin medication safety thresholds

Cases where this rule fires

Open a case to see this rule fire with real inputs, then change the values until it stops.

The Clinical Intelligence Layer — transforming fragmented clinical information into structured intelligence for clinician review and action.

Contact Biod