Synthetic data only. Never enter patient information; nothing is sent or stored. For clinicians. Not FDA cleared.

CPE-003 · Medication safety

MED-SGLT2-001: Expected early eGFR dip after SGLT2i

Expected early eGFR dip after SGLT2i. Evaluates SGLT2i recently initiated is true.

Active rulePriority 104Kidney engine v1.2.0

Condition

  • All of:
  • SGLT2i recently initiated == true
  • reversible eGFR decrease present == true
  • severe acute red flag == false

What it reports

  • Message: An initial reversible eGFR decrease after SGLT2 inhibitor initiation is generally not by itself an indication to discontinue therapy; clinician review remains required.

Evidence

  • R1KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Disease: Improving Global Outcomes (KDIGO), 2024.Supports: CKD definition and chronicity CGA classification albuminuria confirmation risk prediction referral medication stewardship progression monitoring

Cases where this rule fires

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