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CPE-011 · Etiologic patterns

AN-10: Iron-deficiency pattern

Iron-deficiency pattern. Evaluates anemia present.

Active rulePriority 3Anemia engine v1.0.0

Condition

  • anemia present
  • ferritin < 30 ng/mL (or < 100 with inflammation) with transferrin saturation < 20%
  • usually microcytic

What it reports

  • Pattern compatible with iron deficiency: see the Iron Deficiency Pattern Engine

Recommended next steps (for physician review)

  • Establish the source of iron loss or poor absorption

Diagnostic boundary

  • Cause still to be found.

Evidence

  • EV-CAMASCHELLA-2015Camaschella C. Iron-deficiency anemia. N Engl J Med. 2015;372(19):1832-1843.Supports: Iron deficiency and anemia of inflammation

Cases where this rule fires

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