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CPE-011 · Etiologic patterns

AN-11: Anemia of inflammation pattern

Anemia of inflammation pattern. Evaluates anemia present.

Active rulePriority 4Anemia engine v1.0.0

Condition

  • anemia present
  • CRP raised or chronic inflammatory disease, infection or malignancy
  • ferritin ≥ 100 ng/mL with transferrin saturation < 20%
  • normocytic or mildly microcytic

What it reports

  • Pattern compatible with anemia of inflammation, possibly with coexisting iron deficiency

Diagnostic boundary

  • Cannot exclude a coexisting deficiency.

Evidence

  • EV-CAMASCHELLA-2015Camaschella C. Iron-deficiency anemia. N Engl J Med. 2015;372(19):1832-1843.Supports: Iron deficiency and anemia of inflammation

Cases where this rule fires

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