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CPE-011 · Etiologic patterns
AN-13: Megaloblastic pattern
Megaloblastic pattern. Evaluates anemia present.
Active rulePriority 3Anemia engine v1.0.0
Condition
- anemia present
- macrocytic
- vitamin B12 < 300 pg/mL or folate low or MMA raised, OR hypersegmented neutrophils
What it reports
- Pattern compatible with vitamin B12 or folate deficiency: see the Vitamin B12 and Folate Pattern Engine
Diagnostic boundary
- Check B12 before folic acid.
Evidence
- EV-DEVALIA-2014Devalia V, Hamilton MS, Molloy AM; British Committee for Standards in Haematology. Guidelines for the diagnosis and treatment of cobalamin and folate disorders. Br J Haematol. 2014;166(4):496-513.Supports: Megaloblastic anemia and its evaluation
Cases where this rule fires
Open a case to see this rule fire with real inputs, then change the values until it stops.
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